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Wednesday, January 29, 2020

Air Quality Essay Example for Free

Air Quality Essay 1. Identify and describe the nature of this issue, the spatial and ecological dimension? Air quality is a measure of the amount of pollutants emitted into the atmosphere and the dispersion potential of an area to dilute those pollutants. It is a massive problem of urban living and remains one of the largest environmental concerns. Spatial dimension relates to how air quality differs between places at different times and under different weather patterns. Increasing population and demand for more goods puts greater pressure on air quality. The human population’s interaction with the environment relates to the ecological dimension. In terms of air quality this relates to the impacts of increased gases and particles associated with transportation, industrial activities, smoking, dust storms from over grazing on marginal land, bush fires and the burning fossil fuels. Many of these activities cause increases in carbon monoxide, ozone, sulphur dioxide, nitrogen dioxide, lead and particles in the atmosphere. People get health problems due to these increases. For example, excessive carbon monoxide levels in the blood stream reduce its ability to transport oxygen. This in turn causes headaches and tiredness. 2. Explain the geographic processes causing the issue Humans are exposed to a number of pollutants , air toxics and particulate matter in the air we breathe and live in. A number of organisations have worked on standards that identify those levels that are safe and those that are not and how these impact on a human’s well being. Pollutants are substances which at high enough levels can cause harm to people and the environment (including plants and animals). Things like sulphur dioxide is from coal, oil burning power stations, mineral ore processing and chemical manufacture. With Sulfur dioxide health issues like the throat and lungs are attacked. People with breathing problems can suffer severe illness . Nitrogen dioxide Is caused from fuel combustion. The throat and lungs are affected with increased levels in the atmosphere. The burning of fossil fuels and motor vehicle emissions increase carbon monoxide levels. Excessive carbon monoxide levels in the blood stream reduce its ability to transport oxygen. This in turn causes headaches and tiredness. Volatile organic compounds are caused by combustion of fuel, motor vehicles and solvent use. With increased levels of VOCs skin irritation, eye irritation and nausea may be caused. It can also be a cancer causing issue. Ozone is formed from nitrogen oxides and hydrocarbons in sunny conditions. It is also released by motor vehicles and industry. The tissues of the throat, lungs and eyes may be irritated. Increased lead levels are as a result of exhaust gases from motor vehicles that use leaded petrol, as well as emissions from smelters. In lead it can get into your lungs and go into your blood stream. It can affect you by shutting down your nervous system and the body will stop producing blood and you will die. Motor vehicles, burning of plant materials and bush fires increase levels of particles in the atmosphere. Breathing difficulties and respiratory diseases may worsen. Some particles may contain cancer causing agents. Air toxics are pollutants that are also hazardous to humans. Air toxics are hydrocarbons and heavy metals. They are of high concern when emitted close to the source. Examples include at industrial sites and heavily used roads. There is a connection with high levels of air toxics to cancer, birth defects, genetic damage and respiratory and nervous system disorders. Particles are liquids or solids found in the air. They can be natural substances all those from fuel burning processes. The most damaging particle is known as PM10. This is due to the fact it can stay in the atmosphere for long periods and also be carried large distances is has been known to increase death rates in areas of high concentrations. 3.Outline some contrasting views of different groups involved in the issue? A major issue associated with air quality is related to traffic congestion. Traffic congestion in Sydney has forced roads to go underground in tunnels. Exhaust fumes are then sent above ground via ‘stacks.’ These stacks are of major concern in the areas where they are located, in particular for the health of humans and animals, as well as the environment. The M5 East tunnel, in particular, has had strong feelings from a number of groups. Originally 3 stacks were to be built on high ground to rid the tunnel of fumes. There were many people against this, so only one 35 metre stack was built without a pollution filter. Some contrasting views are summarised below, from a number of groups: Residents against pollution stacks: (RAPS): Protest, court cases, inquiries, petitions and letters have been written to voice concern about pollution, but little has been done. This group believes they are unhealthy, expensive to run and that the government is not caring about the publics health and safety. Minister for roads (state parliament 2006): The Minster believes that the public’s health is not at risk, because of fresh air is put into the tunnels and air quality levels are always met. He believes standards are constantly monitored and that it is well used by motorists. DR Raymond Kearney- associate professor in dept. of Infectious diseases/Immunology: Acess to clean sir is a human need and right. Your lungs me a barrier between the outside world and your body, the tosic substances from the air that is leaving the tunnel and the air that is in side the tunnels reaches your body via the lungs. The burning of petrol, diesel is one of the most toxic sources.

Tuesday, January 21, 2020

Requirements for Success in an Industry and the Attributes of Successfu

Requirements for Success in an Industry and the Attributes of Successful Leaders In terms of hospitality, leadership is defined as: leading is the process by which a person with vision is able to influence the activities and outcomes of others in a desired way (Walker 543). David P. Norton from Decision Point, Inc says, â€Å"Leadership-the availability of qualified leaders at all levels to mobilize the organization toward its strategy.† Both of these definitions are correct depending on your perception of the word. Leadership has many complexities which result in different types of leadership, individual perceptions of it and many definitions. The hospitality industry finds that leadership is not only a wonderful quality to have, but also a very important tool in managing and running an organization. Leaders are very important and carry with them certain traits that contribute to their success. To leave an impact that many people care about and remember you by is achieved through being a good leader as well as a manger because leadership is pa rt of managing. As a result of the complexities of leadership, there are three types: transactional, situational and transformational leadership. Transactional leadership is viewed as a process by which a leader is able to bring about desired actions from others by using certain behaviors, rewards, or incentives (Walker 543). Basically saying do this for that. The leader promises to exchange something an employee might desire for a task they do for the leader, the coming together of a leader, follower, and situation. For example, the leader might ask that you as a follower achieve certain goals for a bonus. A second type of leadership is situational which ... ... 2004. Hazard Analysis and Critical Control Points (HACCP) Guidelines During one of my food service classes we were to come up with HACCP guidelines for a food. This allowed me to analyze and critique the entire procedure from the point food is received till it is prepared. I learned how important it is to pay attention to the little things involved with food preparation to the obvious. Meal Planning Project This project was done my sophomore year in college. It was a very time consuming project that was challenging and well worth it. The meal planning project gave me a chance to plan a menu for a full day that meets the recommendations in the Dietary Guidelines, the Food Guide Pyramid and the Recommended Dietary Allowances for an individual of your age and sex. The project limited me again with a budget of $4.00 total for the day.

Sunday, January 12, 2020

Combination Therapy in Heart Failure

The ability of the heart to pump blood Is impaired and It can no longer meet the bodys metabolic requirements Table 1 . New York Heart Association Classiflcation of Heart Failure. Remme W], Swedberg K. Guidelines for the diagnosis and treatment of chronic heart failure. European Heart Journal. [Online] 2001; 22(17): 1527-1 560. during the rest or exercisel. By treating HF we try to relieve patients symptoms, Improve their quality of life, prevent hospitalization and most importantly prolong their life. The treatment Includes Improved diet (reduced salt intake), physical activity and pharmacological treatment.There are numerous angiotensin-receptor blockers (ARBs), vasodilators, angiotensin-converting enzyme (ACE) inhibitors Ramipril) and beta-blockers (Carvedilol). We will have a look at the last two classes. They have been PATHOPHYSIOLOGY The previous hemodynamic model was not adequate and was therefore replaced by neurohormonal model, which involves Reninangiotensin-aldosterone-sys tem sympathetic nervous system 1 , (RAAS) 3 is summarized in Figure 1. The activation of RAAS leads to vasoconstriction, oedema and myocardial fibrosis, which are induced by Angiotensin Ill . roven to be very efficient in HF by numerous clinical studies2-4. SYMPTOMS AND SIGNS HF involves many symptoms such as dyspnoea fatigue, and ankle oedema. l The signs of HF are achycardia (>100 beats per minute), tachyarrhythmia, tachypnoea, distended Jugular murmur and S3 and S4 heart sounds. The Figure 1 . pathophysiology of heart failure and different levels of therapeutic intervention. Taken from: Perrenoud J]. Heart failure (Part 1). European Geriatric Medicine. [Online] 2011; 2(3): 159-171. ccurrence of these symptoms and signs depends on One of the earliest neurohormonal changes in HF is the severity of heart failure and whether it is caused sympathetic activation and it has a primary role in vein, peripheral oedema, hepatomegaly, heart by systolic dysfunction or diastolic dysfunction . isease progression. Left ventricular remodeling, cell death and changes in gene expression are believed to be the main mechanisms that induce ejection fraction8-11. Because it is very potent, small myocardial doses of the tablet should be taken at the start of damage nervous stimulation 10. treatment (3. 125mg) twice daily.The dose is Heart failure can be categorized in predominantly gradually increased up to maximum of 50mg twice systolic dysfunction where the emptying of the left daily8. ventricle is not optimal and predominantly diastolic dysfunction where the filling of the left ventricle is Molecular targets ot optimall -6. As mentioned above, its major molecular targets are membrane receptors (?l, ?2 and 01). It acts on ion TREATMENT channels (Ca2+ and K+) as well. Carvedilol inhibits As mentioned above, the disease can be treated cardiac voltage-dependent potassium IKr channels using several different drug classes4.Multidrug with high potency, voltage-dependent calcium therap y is widely used in patients with heart failure. channels as well as Ca2+-permeable transient receptor potential (TRP) family channels in Failure Zealand cardiomyocytes and in vascular smooth muscle Carvedilol Trial) have been conducted to test the ells. Furthermore, a study conducted by (Kikuta et benefits of different combinations of drugs. It was al. , 2006) suggests that the drug blocks ATP- proven that these therapies significantly reduce the sensitive (KATP) and G-protein-activated (KG) risk of mortality and improve the symptoms. otassium However, hyperinsulinemia and hypoglycemia. It is believed implementing multi drug therapy. ACE inhibitors that the KG channel is opened by G protein in can cause hypotension, cough, and worsen the renal response to stimulation of G-protein-coupled function. Cough can cause patient noncompliance, uscarinic acetylcholine receptors in atria and sino- which in turn may result in the need of different drug therapy. Beta-blockers can cause bradyca rdia, channel would result in anti-cholinergic effects in hypotension, fatigue and fluid retention.Also, in the heartl 2. Study patients there with Australian-New are risks diabetes, associated beta-blockers channels. This results in could Pharmacodynamics Carvedilol is a racemic mixture of R and S Carvedilol enantiomers. Both enantiomers show al receptor Carvedilol is a non-selective beta-blocker (?l and inhibition. However, only S enantiomer inhibits ? ?2) has drenoreceptors. It competitively blocks both ?l and vasodilatation and antioxidant effects. Previously it ?2 receptors. The drug reduces high blood pressure be mainly due to the al and ? blockage.The inhibition contraindicated in HF as it has negative ionotropic of al receptor lowers total peripheral vascular effect. However, studies have shown that carvedilol resistance. Hence, it reduces afterload and balances in combination with ACE inhibitors improves the negative ionotropic effect the ? inhibition. As a function of the heart, especially left ventricular result, the stroke volume and cardiac output are al-blocker. elieved that Furthermore, carvedilol it should maintained or even increased. The systemic arterial The effects of carvedilol are summarized in figure pressure is lowered without reducing the renal 3. lood flow13-14. The antioxidant effects carvedilol and some of its metabolites are due to the presence of carbazole moiety (shown in Figure 2). In myocardial cell membrane carvedilol inhibits lipid peroxidation. Moreover, endothelial, vascular and neuronal smooth muscle cells from reactive oxygen species. Metabolite SB209995 is much more potent antioxidant than carvedilol itself. Animal studies have shown (Feuerstein et l. , 1998) heart failure imbalances the production of reactive oxygen species and the oxidant defense mechanism. The consequence is an excess of free radicals.This may result in cytotoxic effects as well as cardiovascular remodelingl 3. Figure 3. Molecular targets, pharmacodyn amics and clinical implications of carvedilol. Cheng J, Kamiya K, Kodama l. Carvedilol: Molecular and Cellular Basis for its Multifaceted Therapeutic Potential. cardiovascular Drug Revvtevs. coniine] 2006; 19(2): 152-71. Therapeutic efficacy Many different controlled clinical studies were made in order to determine the efficacy of carvedilol. The most known are COPERNICUS, CAPRICORN and USCHFS. They have all shown significant reduction in morbidity and mortality in comparison placebol 5-16.COMET investigating the difference between carvedilol and metoprolol efficacy. The study showed that the allcause mortality was lower with carvedilol (34%) Figure 2. Chemical structure of carvedilol (with postulated active sites) and its active metabolites. * denotes the point of assymetry. Taken from: Cheng J, Kamiya K, Kodama l. Carvedilol: Molecular and Cellular Basis for its Multifaceted Therapeutic Potential. cardiovascular Drug Rewtevs. coniine] 2006; 19(2): 152-71. Carvedilol aids lipid met abolism as it prevents the oxidation of low-density lipoproteins (LDL).It is known that LDL has destructive effects endothelial cells. Carvedilol also inhibits the Renin-angiotensin system (RAS). Hence, the production of Angiotensin II is lowered. Furthermore, studies on cardiac rat myocytes showed that carvedilol enhances the production of nitrite. It is therefore believed that it can increase the NO synthesis through some adrenoreceptor independent mechanism. However, the role of excessive amounts of NO in the diseased heart remains unclear 13-14. than with metoprolol (40%) as shown in figure 417. Figure 4.All-cause Mortality between Carvedilol and Metoprolol. Poole-Wilson PA, Swedberg K, Cleland JGF et al. Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol or Metoprolol European Trial (COMET): randomized controlled tnal.

Saturday, January 4, 2020

French Texting - Les Textos Francais

Learning French is one thing, but French on the internet — in chatrooms,  forums, text messaging (SMS), and email can seem like a completely different language. Fortunately, help is at hand. Here are some common French abbreviations, acronyms, and symbols to help you communicate via text, followed by some helpful tips and pointers. French Meaning English 12C4 un de ces quatre one of these days 2 ri 1 de rien youre welcome 6n Cin Movie theater A+@+ plus L8R, laterCUL8R, see you later A12C4 un de ces quatre See you one of these days a2m1@2m1 demain CU2moro, see you tomorrow ALP la prochaine TTFN, ta ta for now AMHA mon humble avis IMHO, in my humble opinion APAPLS plus TTFN, ta ta for now ASV ge, Sexe, Ville ASL, age, sex, location a tt tout lheure see you soon auj Aujourdhui Today b1sur Bien sr Of course BAL Bote aux lettres Mailbox BCP Beaucoup A lot bi1to Bientt RSN, real soon biz bisous kisses bjr Bonjour Hello bsr Bonsoir Good evening C Cest It is C1Blag Cest une blague Its a joke, Just kidding CAD Cest--dire That is, i.e., cb1 Cest bien Thats good C cho Cest chaud Its hot C Cest It is Ch ChezJe sais At the home ofI know ChuChuiChuis Je suis I am C mal1 Cest malin Thats clever, sneaky C pa 5pa Cest pas sympa Thats not nice CPG Cest pas grave INBD, its no big deal Ct CtaitCest tout It wasThats all D100 Descends Get down dacdak Daccord OK DSL Dsol IMS, Im sorry DQP Ds que possible ASAP, as soon as possible EDR croul de rire LOL, laughing out loud ENTKEntouK En tout cas IAC, in any case FAI Fournisseur daccs internet ISP, internet service provider FDS Fin de semaine WE, Wknd, weekend G Jai I have G1id2kdo Jai une ide de cadeau I have a great idea GHT Jai achet I bought GHT2V1 Jai achet du vin I bought some wine G la N Jai la haine H8, hate GspR b1 Jespre bien I hope so Gt Jtais I was J Jai I have Je c Je sais I know Je le saV Je le savais I knew it Jenmar Jen ai marre Im sick of it Je tM Je taime ILUVU, I love you Je vJv Je vais Im going JMS Jamais NVR JSG Je suis gnial Im (doing) great JTM Je taime I love you K7 cassette cassette tape KDO Cadeau Gift KanKand Quand When Ke Que that, what K Quest What is Kel Quel, Quelle Which Kelle Quelle That she Keske Quest-ce que What kestufouKsk tfu Quest-ce que tu fous ? What the hell are you doing? Ki Qui Who Kil Quil That he Koi Quoi What Koi29 Quoi de neuf ? Whats new? Lckc Elle sest casse She left Ls tomB Laisse tomber Forget it Lut Salut Hi M Merci Thanks MDR Mort de rire ROFL mr6 Merci Thx, thanks MSG Message Msg, message now maintenant ATM, at the moment NSP Ne sais pas Dunno o Au In the, at the Ok1 Aucun None, not one OQP Occup Busy Ou Ouais Yeah p2k Pas de quoi URW, youre welcome parske Parce que COZ, because p-pitit Peut-tre Maybe PK Parce que Because Pkoi Pourquoi Y, why PoP Pas Not PTDR Pt de rire ROFLMAO, rolling on the floor laughing q-c qqueske Quest-ce que What QDN Quoi de neuf ? Whats new? qq Quelques Some qqn Quelquun Someone raf Rien faire Nothing to do ras Rien signaler Nothing to report rdv Rendez-vous Date, appointment RE (Je suis de) retour, Rebonjour Im back, Hi again ri1 Rien 0, nothing savapa a va pas ? Is something wrong? SLT Salut Hi SNIF Jai de la peine Im sad ss (je) suis I am STP/SVP Sil te/vous plat PLS, please T Tes You are tabitou Thabites o ? Where do you live? tata KS Tas ta casse ? You have your car? tds tout de suite right away ti2 Tes hideux Youre hideous. tjs Toujours Always tkc Tes cass Youre tired. TLM Tout le monde Everyone T nrv ? Tes nerv ? Are you irritated? TOK Tes OK ? RUOK? Are you OK? TOQP Tes occup ? RUBZ? Are you busy? tps temps time, weather Tttt Ttaistout You wereall, every V1 Viens Come vazi Vas-y Go VrMan Vraiment Really X crois, croit believe XLnt Excellent XLNT, excellent y aya Il y a There is, there are French Texting Rules The basic rule of texting is to express yourself with the fewest number of characters possible. This is done in three ways: Using abbreviations, like  TLM  for  Tout Le MondeUsing letters that are pronounced like the desired sounds, like  OQP  for  occupà ©Ã‚  (O - CCU - PÉ)Dropping silent letters, especially at the end of a word, like  parl  for  parle Patterns 1 replaces UN, EN, or IN2 replaces DEC replaces CEST, SEST, SAIS, etc.É replaces AI, AIS, and other spellings of similar soundsK can replace QU (e.g., koi) or CA (kdo)O replaces AU, EAU, AUX, etc.T replaces TES and other spellings of the same sound Tip If all else fails, try reading the symbol out loud.